International Journal of Molecular Medicine

Efficient myoblast expansion for regenerative medicine use.

Jarocha D, Stangel-Wojcikiewicz K, Basta A, Majka M.

Cell Transplantation

A continuous improvement after multiple mesenchymal stem cells transplantations in complete spinal cord injury patient

Stem Cells Translational Medicine

Preliminary Study of Autologous Bone Marrow Nucleated Cells Transplantation in Children With Spinal Cord Injury

Open Journal of Genetics 2013, 3:49-60

Cell therapy of a petient with type III osteogenesis imperfecta caused by mutation in COL1A2 gene and unstable collagen type I.

Majka M, Janeczko M, Gozdzik J, Jarocha D, Augusciak-Duma A, Witecka J, Lesiak M, Koryciak-Komasrka, Sieron AL., Pietrzyk JJ.

Mol Oncol 2013, 7:67-84

Multifunctional protein APPL2 contributes to survival of human glioma cells.

Pyrzynska B, Banach-Orlowska M, Teperek-Tkacz M, Miekus K, Drabik G, Majka M, Miaczynska M.

European Journal of Medical Technologies 2013; 2: 17-23

An improved protocol for adipose tissue-derived stem cell isolation: implications for treatments of bone disorders.

Bobis-Wozowicz S, Millington-Ward S, Zawisz A, Adamus T, Konieczny P, Majka M.

Endokrynol Pol. 2013;64:248-54.

The role of insulin-like growth factor 1, receptor activator for nuclear factor ?B ligand ? osteoprotegerin system, interleukin 6 and 1? in post-transplantation bone metabolic disease in childhood.

Neurourol Urodyn. 2013 Apr 19. doi: 10.1002/nau.22404.

Autologous Muscle-Derived Cells for the Treatment of Female Stress Urinary Incontinence: A 2-Year Follow-Up of a Polish Investigation.

Stangel-Wojcikiewicz K, Jarocha D, Piwowar M, Jach R, Uhl T, Basta A, Majka M.

Cell Death and Disease, 2013 doi: 10.1038/cddis.2012.199

The decreased metastatic potential of rhabdomyosarcoma cells obtained through MET receptor downregulation and the induction of differentiation.

Miekus K, Lukasiewicz E, Jarocha D, Sekula M, Drabik G, Majka M.

Circ Cardiovasc Imaging. 2013 6:320-8.

Infarct Size Determines Myocardial Uptake of CD34+ Cells in the Peri-Infarct Zone: Results from a Study of 99mTc-extamatazime-labeled Cells Visualization Integrated with Cardiac Magnetic Resonance Infarct Imaging.

Musialek P, Tekieli L, Kostkiewicz M, Miszalski-Jamka T, Klimeczek P, Mazur W, Szot W, Majka M, Banys RP, Jarocha D, Walter Z, Krupinski M, Pieniazek P, Olszowska M, Zmudka K, Pasowicz M, Kereiakes DJ, Tracz W, Podolec P, Wojakowski W.

Oncol Rep. 2012 28:1903-9. doi: 10.3892/or.2012.1996.

17AEP-GA, an HSP90 antagonist, is a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion.

Mediators Inflamm. 2012;2012:564027. doi: 10.1155/2012/564027.

Mobilization of CD34+CXCR4+ stem/progenitor cells and the parameters of left ventricular function and remodeling in 1-year follow-up of patients with acute myocardial infarction.

Antioxid Redox Signal. 2012 Jan 15;16(2):113-27. Epub 2011 Oct 19.

Heme oxygenase-1 inhibits myoblast differentiation by targeting myomirs.

Kozakowska M, Ciesla M, Stefanska A, Skrzypek K, Was H, Jazwa A, Grochot-Przeczek A, Kotlinowski J, Szymula A, Bartelik A, Mazan M, Yagensky O, Florczyk U, Lemke K, Zebzda A, Dyduch G, Nowak W, Szade K, Stepniewski J, Majka M, Derlacz R, Loboda A, Dulak J, Jozkowicz A.

Oncol Rep. 2011 Aug;26(2):447-53. doi: 10.3892/or.2011.1321. Epub 2011 May 26.

Fenofibrate attenuates contact-stimulated cell motility and gap junctional coupling in DU-145 human prostate cancer cell populations.

Przegl Lek. 2011;68(1):40-3.

[Fetal CD34+ cells isolated from maternal blood and cytogenetics array as potential tools in screening, non-invasive prenatal diagnosis?preliminary research].

Grabowska A, Madetko-Talowska A, Janeczko M, Majka M, Pietrzyk JJ.

Folia Histochem Cytobiol. 2010 Dec;48(4):671-7.

Differential expression of Snail1 transcription factor and Snail1-related genes in alveolar and embryonal rhabdomyosarcoma subtypes.

M, Lukasiewicz E, Miekus K, Jarocha D, Majka M.

Folia Histochem Cytobiol. 2010 Dec;48(4):611-7.

The presence of B7-H4+ macrophages and CD25+CD4+ and FOXP3+ regulatory T cells in the microenvironment of nasal polyps ? a preliminary report.

Dutsch-Wicherek M, Tomaszewska R, Lazar A, Strek P, Wicherek L, Kijowski J, Majka M.

Exp Hematol. 2011 Jun;39(6):686-696.e4. Epub 2011 Mar 21.

Genetically modified adipose tissue-derived mesenchymal stem cells overexpressing CXCR4 display increased motility, invasiveness, and homing to bone marrow of NOD/SCID mice.

Bobis-Wozowicz S, Miekus K, Wybieralska E, Jarocha D, Zawisz A, Madeja Z, Majka M.

J Nucl Cardiol. 2011 Feb;18(1):104-16. Epub 2010 Dec 14.

Randomized transcoronary delivery of CD34(+) cells with perfusion versus stop-flow method in patients with recent myocardial infarction: Early cardiac retention of ??(m)Tc-labeled cells activity.

Musialek P, Tekieli L, Kostkiewicz M, Majka M, Szot W, Walter Z, Zebzda A, Pieniazek P, Kadzielski A, Banys RP, Olszowska M, Pasowicz M, Zmudka K, Tracz W.

2010 Oct 5;8:116.

The frequency of CD25+CD4+ and FOXP3+ regulatory T cells in ectopic endometrium and ectopic decidua. Reprod Biol Endocrinol.

Basta P, Majka M, Jozwicki W, Lukaszewska E, Knafel A, Grabiec M, Stasienko E, Wicherek L.

Ginekol Pol. 2010 May;81(5):378-81.

Adult stem cells therapy for urine incontinence in women.

Folia Histochem Cytobiol. 2010 Jan 1;48(1):104-11.

Role of I-TAC-binding receptors CXCR3 and CXCR7 in proliferation, activation of intracellular signaling pathways and migration of various tumor cell lines.

Miekus K, Jarocha D, Trzyna E, Majka M.

Folia Histochem Cytobiol. 2009 Jan;47(3):485-9.

Inhibition of rhabdomyosarcoma?s metastatic behavior through downregulation of MET receptor signaling.

Lukasiewicz E, Miekus K, Kijowski J, Drabik G, Wilusz M, Bobis-Wozowicz S, Majka M.

J Physiol Pharmacol. 2009 Sep;60(3):161-6.

High anti tumor activity against rhabdomyosarcoma cells and low normal cells cytotoxicity of heat shock protein 90 inhibitors, with special emphasis on 17-[2-(pyrrolidin-1-yl)ethyl]-aminno-17-demethoxygeldanamycin.

Lukasiewicz E, Miekus K, Kijowski J, Gozdzik J, Wilusz M, Bobis-Wozowicz S, Wiecha O, Majka M.

2009 Apr;61(4):303-12.

The characterization of the subpopulation of suppressive B7H4(+) macrophages and the subpopulation of CD25(+) CD4(+) and FOXP3(+) regulatory T-cells in decidua during the secretory cycle phase, Arias Stella reaction, and spontaneous abortion ? a preliminary report. Am J Reprod Immunol.

Wicherek L, Basta P, Pitynski K, Marianowski P, Kijowski J, Wiatr J, Majka M.

Eur Heart J. 2009 Jun;30(11):1313-21. Epub 2009 Feb 10.

REGENT Investigators. Intracoronary infusion of bone marrow-derived selected CD34+CXCR4+ cells and non-selected mononuclear cells in patients with acute STEMI and reduced left ventricular ejection fraction: results of randomized, multicentre Myocardial Regeneration by Intracoronary Infusion of Selected Population of Stem Cells in Acute Myocardial Infarction (REGENT) Trial.

Am J Reprod Immunol. 2009 Feb;61(2):136-46.

Changes in the subpopulation of CD25+ CD4+ and FOXP3+ regulatory T cells in decidua with respect to the progression of labor at term and the lack of analogical changes in the subpopulation of suppressive B7-H4 macrophages?a preliminary report.

Galazka K, Wicherek L, Pitynski K, Kijowski J, Zajac K, Bednarek W, Dutsch-Wicherek M, Rytlewski K, Kalinka J, Basta A, Majka M.

]. Przegl Lek. 2009;66(9):471-8.

Angiogenesis in different clinical phases of chronic myeloid leukemia.

Folia Histochem Cytobiol. 2008;46(3):307-14.

Adventage of mesenchymal stem cells (MSC) expansion directly from purified bone marrow CD105+ and CD271+ cells.

Jarocha D, Lukasiewicz E, Majka M.

Pediatr Transplant. 2009 Sep;13(6):760-5. Epub 2008 Oct 25.

Rapid full engraftment and successful immune reconstitution after allogeneic hematopoietic stem cell transplantation with reduced intensity conditioning in Omenn syndrome.

, Czogala W, Skoczen S, Krasowska-Kwiecien A, Wiecha O, Mordel A, Lesko E, Majka M, Kowalczyk D, Zembala M.

Arch Immunol Ther Exp (Warsz). 2008 Jul-Aug;56(4):257-66. Epub 2008 Jul 29.

Role of the Wnt/beta-catenin network in regulating hematopoiesis.

Wilusz M, Majka M.

Eur J Nucl Med Mol Imaging. 2008 Oct;35(10):1929-30. Epub 2008 Aug 6.

Early myocardial engraftment of autologous CD34+ cells administered transcoronary via a physiological cell-delivery system.

Musialek P, Kostkiewicz M, Banys RP, Tekieli L, Majka M, Pasowicz M, Tracz W.

Anticancer Res. 2008 Jan-Feb;28(1A):187-92.

Human monocytes both enhance and inhibit the growth of human pancreatic cancer in SCID mice.

B, Baj-Krzyworzeka M, Majka M, Stankiewicz D, Zembala M.

Kardiol Pol. 2008 Jan;66(1):73-7.

Visualisation of early engraftment of transcoronary applied CD34+ cells in the infarct border zone.

Front Biosci. 2008 Jan 1;13:1271-80.

The biological role of HGF-MET axis in tumor growth and development of metastasis.

Lesko E, Majka M.

Anticancer Drugs. 2007 Nov;18(10):1173-81.

HSP90 antagonist, geldanamycin, inhibits proliferation, induces apoptosis and blocks migration of rhabdomyosarcoma cells in vitro and seeding into bone marrow in vivo.

Lesko E, Gozdzik J, Kijowski J, Jenner B, Wiecha O, Majka M.

Folia Histochem Cytobiol. 2007;45(1):27-32.

Evidence that platelet-derived microvesicles may transfer platelet-specific immunoreactive antigens to the surface of endothelial cells and CD34+ hematopoietic stem/ progenitor cells?implication for the pathogenesis of immune thrombocytopenias.

Folia Histochem Cytobiol. 2006;44(4):215-30.

Mesenchymal stem cells: characteristics and clinical applications.

Bobis S, Jarocha D, Majka M.

Folia Histochem Cytobiol. 2006;44(3):155-64.

SDF-1 alone and in co-operation with HGF regulates biology of human cervical carcinoma cells.

Majka M, Drukala J, Lesko E, Wysoczynski M, Jenson AB, Ratajczak MZ

Methods Mol Biol. 2006;332:103-14.

Biological role of the CXCR4-SDF-1 axis in normal human hematopoietic cells.

Majka M, Ratajczak MZ.

Kardiol Pol. 2006 May;64(5):489-98; discussion 499.

Transcoronary stem cell delivery using physiological endothelium-targeting perfusion technique: the rationale and a pilot study involving a comparison with conventional over-the-wire balloon coronary occlusions in patients after recent myocardial infarction.

Arch Immunol Ther Exp (Warsz). 2006 Mar-Apr;54(2):121-35. Epub 2006 Mar 28.

The migration of bone marrow-derived non-hematopoietic tissue-committed stem cells is regulated in an SDF-1-, HGF-, and LIF-dependent manner.

Kucia M, Wojakowski W, Reca R, Machalinski B, Gozdzik J, Majka M, Baran J, Ratajczak J, Ratajczak MZ.

LEUKEMIA 20; 1: 18-28 2006

Cells enriched in markers of neural tissue-committed stem cells reside in the bone marrow and are mobilized into the peripheral blood following stroke.

Kucia M; Zhang YP; Reca R.

EUROPEAN HEART JOURNAL 2006 27; 3: 283-289.

Mobilization of CD34(+), CD117(+), CXCR4(+), c-met(+) stem cells is correlated with left ventricular ejection fraction and plasma NT-proBNP levels in patients with acute myocardial infarction.

Wojakowski W; Tendera M; Zebzda A

LEUKEMIA 2006: 20; 5: 857-869

A population of very small embryonic-like (VSEL) CXCR4(+)SSEA-1(+)Oct-4(+) stem cells identified in adult bone marrow.

Kucia M; Reca R; Campbell FR.

Leukemia, in press

BCR-ABL-positive cells secrete angiogenic factors including matrix metalloproteinases and stimulate angiogenesis in vivo in matrigel implants.

Janowska-Wieczorek A., Majka M., Marquez L.A., Turner A.R., Ratajczak M.Z.

Exp. Hematol. in press

Thrombopoietin but not cytokines binding to gp130 protein-coupled receptors activates MAPK p42/44, AKT and STAT proteins in normal human CD34+ cells, megakaryocytes and platelets.

Majka M., Ratajczak J., Vilair G., Janowska-Wieczorek A., Ratajczak M.Z.

Exp. Hematol., 30: 450-459, 2002

Platelet-dirived microparticles stimulate proliferation, survival, adhesion, and chemotaxis of hematopoietic cells.

Baj-Krzyworzeka M., Majka M., Pratico D., Ratajczak J., Vilair G., Kijowski J., Reca R., Janowska-Wieczorek A., Ratajczak M.Z.

Eur. J. Haematol. 67:1-12

New T-lymphocytic cell lines for studying cell infectability by human immunodeficiency virus.

Rozmyslowicz T, Kijowski J, Conover D.O., Majka M, Baj-Krzyworzeka M, Reca R, Libura J.J., Gaulton G.N., Ratajczak M.Z.

Br. J. Haematol. 115:195-204.

Biologikal significance of MAPK, AKT and JAK-STAT protein activation by various erythropoietin factors in normal human early erythroid cells.

Ratajczak J, Majka M, Kijowski J, Baj-Krzyworzeka M, Zhing K. P, Marquez L. A., Janowska-Wieczorek A, Ratajczak M.Z.

Blood 98:3143-3149.

Platelet-derived microparticles bind to hematopoietic stem/progenitor cells and enhance their engraftment.

. Janowska-Wieczorek A. Majka M. Kijowski J. Baj-Krzyworzeka M. Reca R. Turner AR. Ratajczak J. Emerson SG. Kowalska MA. Ratajczak MZ.

Histochem. Cytobiol. 39(3):235-244, 2001

Biological significance of chemokine receptor expression by normal human megakaryoblasts.

Majka M., Ratajczak J., Baj-Krzyworzeka M., Kijowski J., Reca R., Kubiczek K., Ratajczak M.Z.

Stem Cells,19(5):453-466, 2001.

The SDF-1-CXCR4 axis stimulates VEGF secretion and activates integrins but does not affect proliferation and survival in lymphohematopoietic cells.

Kijowski J., Baj-Krzyworzeka M., Majka M., Reca R., Marquez L.A., Christifidou-Solomidou M., Janowska-Wieczorek A., Ratajczak M.Z.

Platelets, 6:325-332, 2001

In vitro expansion of human megakaryocytes as a tool for studying megakaryopoiesis.

Majka M, Baj-Krzyworzeka M, Kijowski J, Reca R, Ratajczak J, Ratajczak MZ.

Stem Cells, 19(2):99-107, 2001.

Autocrine/paracrine mechanisms in human hematopoiesis.

Janowska-Wieczorek A, Majka M., Ratajczak J, Ratajczak MZ.

Blood, 97:3075-3085, 2001.

Numerous growth factors, cytokines and chemokines are secreted by human CD34+ cells, myeloblasts, erythroblasts and megakaryoblasts and regulate normal hematopoiesis in an autocrine/paracrine manner.

Majka M, Janowska-Wieczorek A, Ratajczak J, Ehrenman K, M.A. Kowalska, Emerson SG, Ratajczak MZ.

Transplantation 71:1003-1007, 2001

Heparinized cadaveric organ donors (HCOD) ? a potential source of hematopoietic cells from transplantation and gene therapy.

Machalinski B, Kijowski J, Marlicz W, Gontarewicz A, Markiewski M, Paczkowski M, Kopkowski A, Majka M, Ostrowski M, Ratajczak M.Z.

J. A I D S 23 (3): 2000

MIP-1 beta induced heterelogous desensitization of CXCR4 mediated signaling on early lineage B cells in human bone marrow.

Honczarenko M, Mathlas C, Majka M, Glodek A, Pietrzkowski Z, Ratajczak MZ, Silberstein LE.

Blood, 2001 97: 638-64

Investigating the platelet sparing mechanism of Paclitaxel/Carboplatin combination chemotherapy.

Pertussini E., Ratajczak J., Majka M., VaughanD., Ratajczak M.Z., Gewirtz A.M.

Blood, 2000, 96, 4142-4151.

Majka M., Janowska-Wieczorek A., Ratajczak J., Kowalska M.A., Vilaire G., Pan Z.K., Honczarenko M., Marquez L.A., Poncz M., Ratajczak M.Z.

Majka M., Janowska-Wieczorek A., Ratajczak J., Kowalska M.A., Vilaire G., Pan Z.K., Honczarenko M., Marquez L.A., Poncz M., Ratajczak M.Z.

Exp. Hematol., 28, 1334-1342 2000

The limited infectability by R5 HIV of CD34+ cells from thymus, cord and peripheral blood and bone marrow is explained by their ability to produce beta-chemokines.

Majka M., Rozmyslowicz T., Ratajczak J., Pietrzkowski Z., Gaulton G.N., Janowska-Wieczorek A., Ratajczak M.Z.

Blood 96:50-7, 2000

Stromal cell-derived factor-1 and macrophage-derived chemokine: 2 chemokines that activate platelets.

Kowalska M.A., Ratajczak M.Z, Majka M., Jin J., Kunapuli S., Brass L., Poncz M.

Leukemia 2000, 14, 1821-1832.

Biological significance of the expression of HIV related chemokine coreceptors (CCR5 and CXCR4) and their ligands by human hematopoietic cell lines.

Majka M., Rozmyslowicz T., Honczarenko M., Ratajczak J., Wasik M., Gaulton G.N.,.Ratajczak M.Z.

Eur. J. Haematol. 64:164-172, 2000.

Binding of stromal derived factor-1a (SDF-1a) to CXCR4 chemokine receptor in normal human megakaryoblasts but non in platelets induces phosphorylation of mitoge-activated protein kinase p42/44 (MAPK), ELK-1 transcription factor and serine/threonin kinase AKT.

Majka M., Ratajczak J., Kowalska M.A., Ratajczak M.Z.

Folia Histochem. Cytobiol. 38(2):53-63, 2000

Expression, regulation and function of AC133 a putative cell surface marker of primitive human haematopoietic cells.

Majka M., J.Ratajczak, B.Machalinski, A.Carter, D.Pizzini, M.A.Wasik, A.M.Gewirtz and M.Z.Ratajczak.

Stem Cells 18:128-138, 2000.

The role of HIV-related chemokine receptors and chemokines in human erythropoiesis in vitro.

Majka M., Ratajczak J., Lee B., Honczarenko M., Douglas R., Kowalska M.A., Silberstein L., Gewirtz A.M., Ratajczak M.Z.

J. Clin. Invest. 104:1739-1749, 1999.

Bone marrow CD34+ cells and megakaryoblasts secrete b-chemokines that block infection of hematopoietic cells by M-tropic R5 HIV

Majka M., Rozmyslowicz T., Lee B., Murphy S.L., Pietrzkowski Z., Gaulton G.N., Silberstein L., Ratajczak M.Z.

Annals of Transplant. 4(2):23-30, 1999

Short-term storage of human haematopoietic cells. Infuence of the air and deoxyribonuclease I

Machalinski B., Szolomicka P., Kijowski J., Baskiewicz M., Karbicka A., Byra E., Majka M., Giedrys-Kalemba S., Ratajczak M.Z.

Annals of Transplant. 4(1):22-30, 1999.

Evidence that human haematopoietic stem cells (HSC) do not reside within the CD34+KIT- cell population.

Ratajczak J.. Machalinski B., Majka M., Kijowski J., Marlicz W., Rozmyslowicz T., Ostrowski M., Ratajczak M.Z.

Folia Histochemica et Cytobiologica. 36(2):61-6, 1998.

A novel serum free system for cloning human megakaryocytic progenitors (CFU-Meg). The role of thrombopoietin and other cytokines on bone marrow and cord blood CFU-Meg growth under serum free conditions.

Ratajczak J., Machalinski B., Samuel A., Pertusini E., Majka M., Czajka R., Ratajczak M.Z.

Annals of Transplantation. 3(3):5-13, 1998

In vivo and in vitro studies on the toxicity of Hoechst 33342 (Ho342). Implications for employing Ho342 for the isolation of haematopoietic stem cells.

Machalinski B., Wiszniewska B., Baskiewicz M.., Marchlewicz M., Majka M.. Wenda-Rozewicka L. , Ratajczak M.Z.

Acta Haematol. Polonica 4:461:468, 1998

The influence of ammonium chloride on the clonogeneic growth of human haematopoietic marrow, cord blood progenitors and cells from selected leukemic cell lines.

Machalinski B., Majka M., Ratajczak M.Z.

Oncol. Pol. 3-4:117-123, 1998.

Ex vivo expansion of human megakaryocytic progenitors as a method for ameliorating chemotherapy or haematopoietic transplant related thrombocytopenia.

Honczarenko M., Machalinski B., Marlicz W., Majka M., Kijowski J., Paczkowski M., Ratajczak J., Ratajczak M.Z.

Oncol. Pol. 3-4:111-115, 1998.

Protooncogen c-MYB regulates telomerase activity in chronic myeloid leukemia cells. Preliminary report.

Majka M.,.Honczarenko M, Kijowski J., Paczkowski M., Gontarewicz A., Paczkowska E., Ratajczak M.Z.

Br. J. Haematol. 103:969-979, 1998.

Role of vascular endothelial growth factor (VEGF) and placenta-derived growth factor (PlGF) in regulating human haematopoietic cell growth.

Ratajczak M.Z., Ratajczak J., Machalinski B., Majka M., Marlicz W., Carter A., Pietrzkowski Z., Gewirtz A.M.